Genetic associations with performance on a behavioral measure of distress intolerance

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Genetic associations with performance on a behavioral measure of distress intolerance.

Both theory and empirical evidence support possible associations between two candidate genetic polymorphisms (SLC6A4 5-HTTLPR l/s and COMT Val(158)Met--rs4680 variants) and emotion-regulation difficulties. One particular form of emotion-regulation difficulty, distress intolerance, has been measured using a behavioral assessment in youth; data indicate a relationship with poor psychological func...

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BACKGROUND AND OBJECTIVES Distress intolerance is a core element of many models of psychopathology and is related to a range of disorders and maladaptive behaviors. However, research on distress intolerance has been hampered by inconsistency in its assessment. Moreover, recent perspectives suggest that distress intolerance varies based on the domain of distress, highlighting the need for a meas...

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ژورنال

عنوان ژورنال: Journal of Psychiatric Research

سال: 2012

ISSN: 0022-3956

DOI: 10.1016/j.jpsychires.2011.09.017